This week, LevelFields AI alerts spotlighted significant market movements. CGTX led the gains with a 27.5% one-day surge after positive phase two results for its Alzheimer’s therapy. Close behind, NXPL soared 25% in a single day, fueled by a 15.5% stock buyback announcement. APLT also saw a 12% increase following news of its CEO's departure.

On the downside, HYZN fell over 40% after announcing mass layoffs, while GOEV dropped 32% for the same reason, marking them as the week’s biggest losers.

Novo Nordisk Faces Setback as Shares Plunge 20%

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Novo Nordisk shares dropped 20% after disappointing trial results for its experimental weight-loss drug, CagriSema. The late-stage trial showed a 22.7% weight reduction, falling short of the 25% previously anticipated. Despite outperforming Wegovy in weight reduction, the results dampened expectations for the drug as a next-generation obesity treatment. Meanwhile, competitor Eli Lilly (LLY) saw a 5% rise in its stock, bolstered by its superior performance in earlier head-to-head trials.

The FDA also announced the shortage of GLP1s that allowed generic knock-off versions of the drug to be sold by telehealth providers like Hims & Hers (HIMS) is now over. This means the companies will no longer be able to offer them come the end of Q1 2025. HIMS stock, which attributes 1/3 of its 77% revenue growth to generic GLP1s sold off 12% on the news. The stock was already down after Amazon announced the launch of generic hair loss and ED drugs that will compete with Hims & Hers.

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FedEx Rises Amid Freight Spinoff and Privatization Prospects

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FedEx shares climbed 8% after announcing plans to spin off its freight trucking division, a move expected to unlock $20 billion in shareholder value. The restructuring aims to streamline operations by merging its Express and Ground units.

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Adding to its momentum, FedEx stands to benefit from President-elect Donald Trump’s proposal to privatize the U.S. Postal Service. The potential policy could increase market opportunities for private delivery giants like FedEx and UPS, particularly following FedEx’s loss of a major USPS contract earlier this year.

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